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  Access statistics : Table of Contents
   2016| June-September  | Volume 7 | Issue 2  
    Online since January 16, 2017

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Risk Factors for Type 2 Diabetes in Bangladesh: A Systematic Review
T Sal-sabil, A Islam, SM Shariful Islam
June-September 2016, 7(2):5-5
Diabetes is one of the most significant public health challenge in developing countries. The risk factors for diabetes are poorly understood among the Bangladeshi population. This study aimed to explore the potential risk factors for type 2 diabetes in Bangladesh. A systematic review was performed. Studies describing the risk factors for type 2 diabetes in Bangladesh published between 1994 to 2014 were included and summarized. Of the 35 studies identified, we included 14 studies that met the inclusion criteria. The prevalence of diabetes was higher among females compared to males. Fourteen common risk factors for diabetes in Bangladesh were identified, namely increased age, obesity, waist- hip ratio, social class, hypertension, family history, sedentary life style among others. The p otential risk factors differed by urban-rural areas and by gender. Several risk factors contribute to the increasing prevalence of type 2 diabetes. Our reviews suggest "metabolically-disadvantageous" body composition of more abdominal and visceral fat in Bangladeshi adults might cause higher diabetes risk at a lower BMI compared to Western population. Preventive strategies targeting to control risk factors for diabetes is a priority public health issue and should be considered for early intervention by clinicians and policy makers.
[ABSTRACT]   Full text not available  [PDF]
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Comprehensive Management of Type 1 Diabetes in a Marginalized Population in Northern India: a Seven Year Retrospective Review
S Gupta, JK Gupta, S Kumar, S Tarun, S Dayamurtyananda, GD Ogle
June-September 2016, 7(2):2-2
Indian children with type 1 diabetes (T1D) from resource-poor families often have poor prognoses due to unavailability or unaffordability of care. We utilized a team-based approach to treat marginalized T1D children with multiple daily insulin injection (MDI) basal bolus regimen. In this study, a chart review of all 48 patients treated from 2006-2014 were included. A team-based approach comprising a physician, a diabetes educator and a community health worker were used. All patients were administered MDI of glargine and short-acting human insulin. Extensive diabetes self-management education tailored to culture, language, and literacy level was provided. Carbohydrate counting of local foods was introduced with patients utilizing home blood glucose monitoring. The structured program included home visits, telephone and internet support and group meetings. Age (Mean ± SD) at enrolment was 13.9 ± 4.7 years (n=48), with 26 males (54%). For 25 patients followed for ≥ 3 years, HbA1c at baseline and years 1, 2 and 3 was (Mean ± SD) 13.0 ± 1.0%, (119 ± 11 mmol/mol) 9.0 ± 2.0% (75 ± 22 mmol/mol) 8.2 ± 1.5% (66 ± 17 mmol/mol) and 8.3 ± 1.4% (67 ± 15 mmol/mol), respectively and BMI improved from (Mean ± SD) 15.4 ± 2.4 to 19.0 ± 2.9 kg/m2. The most recent median HbA1c for all patients was 8.6% (70 mmol/mol). There were no hospital readmissions with ketoacidosis or severe hypoglycemia, and one death from unknown causes. Integral to the program's success was provision of essential diabetes supplies and intensive locally-relevant diabetes education, including innovative approaches such as an internet-based support group. Our findings suggest that it is feasible to achieve successful and sustainable T1D management in an indigent population in rural India.
[ABSTRACT]   Full text not available  [PDF]
  2,195 416 -
Clinical experience with ambulatory glucose profile for monitoring glucose control in newly diagnosed type 2 diabetes mellitus on early intensive insulin therapy
BS Ratna, S Thangamani, R Subashini, R Unnikrishnan, V Mohan
June-September 2016, 7(2):1-1
In this case reports of four patients newly diagnosed with type 2 diabetes mellitus (T2DM) in whom a short course of insulin was given along with oral hypoglycemic agents for a short period in order to correct glucotoxicity. The Ambulatory Glucose Profile (AGP) was initiated to study the effect of our prescription at initial visit on subsequent glycemic control and to further adjust treatment at the end of two weeks. We also compared the area under the curve (AUC) for glucose on 2nd day of treatment with that of the 13th day (using the trapezoid method) so as to obtain a quantitative measure of the response to early and aggressive treatment with insulin in this group of newly diagnosed patients. The 1st and 14th day were not considered for analysis as the data was incomplete due to differing times of insertion and removal of the sensor.
[ABSTRACT]   Full text not available  [PDF]
  2,149 420 -
Association between serum chemerin level and severity of coronary artery disease in Egyptian patients with type 2 diabetes
N Lachine, FZ ElSewy, MH Megallaa, M Sadaka, G Khalil, K Rohoma, NG Amin
June-September 2016, 7(2):4-4
The objective of this study was to assess the relationship between serum chemerin level and the severity of coronary artery disease (CAD) in Egyptian patients with type 2 diabetes T2DM. The study included 160 subjects; divided into 4 equal groups; T2DM patients having CAD, CAD patients without diabetes, T2DM patients without CAD and a healthy control group. Serum chemerin level, and hs-CRP were measured and the severity of CAD was assessed using SYNTAX score. Serum chemerin was significantly higher in patients with CAD (p<0.001), with no difference however between diabetic and non-diabetic subjects (p= 0.16). Our results showed a significant positive correlation between serum chemerin and waist circumference (p=0.024) as well as waist to hip ratio (p=0.044). A significant association has been observed between the severity of CAD and each of serum chemerin (p <0.001) and hs-CRP (p =0.04). We report here a positive correlation between serum chemerin level and cardio-metabolic disease, with a significant association between serum chemerin concentration and severity of CAD in Egyptian patients with T2DM.
[ABSTRACT]   Full text not available  [PDF]
  2,066 384 -
Microalbuminuria as an index of diabetic nephropathy among chronic diabetic patients in Gumel, North Western Nigeria
HA Halliru, B Musa, SD Dahiru, YA Koki, S Adamu, SM Adamu
June-September 2016, 7(2):3-3
Diabetes remains a significant health and socio-economic challenge for patients and for health care system. Microalbuminuria (MA) has been indicated as a risk factor for chronic diabetic renal complication. This study aimed at assessing the microalbuminuria level as an index of nephropathy by determining urinary creatinine and albumin among chronic diabetic patients with histor y of five years and above attending the clinic irrespective of age and gender. In this clinical prospective study, 100 chronic diabetic patients and 100 controls were recruited, blood samples were collected for the estimation of Fasting blood sugar by Glucose Oxidase method. Urine samples were also collected for the estimation Albumin and creatinine by Immuno-turbidimetry and Jaffe's methods respectively. The MA was evaluated as Albumin/creatinine. Student t-test was used to compare the means. Mean of MA in diabetics was (58.9±10.2) while Mean of MA in controls was (19.8±3.0) which is statistically significant (p<0.05). The overall prevalence of MA was 34.00% being statistically significant with age of the subjects while statistically non-significant with gender. However, this study signifies relationship between Diabetes and Microalbuminuria.
[ABSTRACT]   Full text not available  [PDF]
  2,029 389 -