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CASE REPORT
Year : 2021  |  Volume : 12  |  Issue : 3  |  Page : 368-370

Pitfalls in estimation of glycosylated hemoglobin: A rare hemoglobin variant—Hb Hope


1 Department of Endocrinology and Diabetes, Institute of Musculo-skeletal Disorders & Orthopaedics, Medanta The Medicity, Gurgaon, Haryana, India
2 Institute of Musculo-skeletal Disorders & Orthopaedics, Medanta The Medicity, Gurgaon, Haryana, India

Correspondence Address:
Dr. Anu Mathew
Department of Endocrinology and Diabetes, Medanta The Medicity Hospital, Gurugram 122001, Haryana.
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JOD.JOD_2_21

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Hemoglobin (Hb) Hope is a rare Hb variant which is clinically silent but causes spuriously high glycated hemoglobin (HbA1c). We report a case of a 45-year-old gentleman, planned for elective total hip replacement, who presented with very high HbA1c with normal blood glucose and fructosamine levels. With the suspicion of erroneous HbA1c, an Hb electrophoresis was done, and he was found to have a rare hemoglobin variant called Hb Hope. We also reviewed almost all case reports of Hb Hope variant causing spuriously high HbA1c levels from India.


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