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Year : 2016  |  Volume : 7  |  Issue : 3  |  Page : 2

Hospital-based prevalence of chronic kidney disease among the newly registered patients with diabetes

1 Department Epidemiology and Biostatistics, BIRDEM General Hospital Dhaka, Bangladesh
2 Community Medicine, Ibrahim Medical College, Dhaka, Bangladesh
3 Department of Applied Statistics, East West University, Dhaka, Bangladesh
4 Health Economics Unit, Diabetic Association of Bangladesh, Dhaka, Bangladesh
5 Director General, BIRDEM General Hospital, Dhaka, Bangladesh
6 BIRDEM Academy, Dhaka, Bangladesh
7 President, Diabetic Association of Bangladesh, Dhaka, Bangladesh

Correspondence Address:
P A Khanam
Principal Research Officer, Department Epidemiology and Biostatistics BIRDEM General Hospital, Dhaka, Bangladesh

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Source of Support: None, Conflict of Interest: None

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Chronic kidney disease (CKD) is proved to be a major public health issue worldwide and an important contributor to the overall non-communicable disease burden. It increases risk of mortality, end-stage renal disease and accelerated cardiovascular disease (CVD). Diabetes is the biggest contributor to CKD and end stage renal disease (ESRD). In Bangladesh, very few data on CKD is available. This study aimed to estimate the prevalence of CKD among the newly registered diabetic patients at BIRDEM (Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders), a referral center for diabetes in Bangladesh. Methods: The study included all diabetic patients aged 18 - 80 years and were registered in the year 2012. Socio-demographic (age, sex, residence, income, literacy), clinical (obesity, blood pressure) and biochemical (blood glucose, lipids, eGFR) information were collected from the BIRDEM registry. CKD was defined according to the K/ DOQI guidelines. Results: A total of 1317 type 2 diabetic patients of age 18 to 80 years were studied. Of them, men and women were 54.7% and 45.3%, respectively. The overall prevalence of CKD (eGFR ≤60 (ml/min/m2)) was 13.9%. The prevalence was significantly higher in women than men (21.3 v. 7.8%, p<0.001). Higher prevalence was also observed in illiterate than literate (19.8 v. 11.8%, p <0.001) group. The patients with systolic hypertension (sHTN) had also significantly higher prevalence (sHTN ≥140 v. <140 mmHg: 19.9 v. 12.6%, p=0.004). The mean (SD) age of the CKD was found significantly higher than the non-CKD [53.1(11.1) vs. 46.0 (11.2)y, p<0.001] group. Logistic regression estimated that the risk for female sex, older age (>50y), higher sBP (≥140mmHg) and taking oral hypoglycemic agent (OHA) were significant. Conclusions: Thus, the study concludes that the prevalence of CKD among the newly registered diabetic patients is quite high in Bangladesh. The female diabetic patients with older age and with higher SBP bear the brunt of CKD. Considering high prevalence of CKD with severe lifelong complications it is of utmost importance for early detection and intervention at the primary health care (PHC) level.

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