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Year : 2015  |  Volume : 6  |  Issue : 3  |  Page : 4

Study of hearing function in type-2 diabetes with reference to common risk factors

Department of Physiology, All India Institute of Medical Sciences, Bhopal, India

Correspondence Address:
A K Pandey
Department of Physiology, All India Institute of Medical Sciences, Bhopal, India

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Source of Support: None, Conflict of Interest: None

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Type 2 diabetes mellitus is the most prevalent non-communicable disease having progressive irreversible sensorineural hearing loss as sequela. Contemporary diabetes management needs to pay attention to timely detect and check or mitigate hearing loss which may seriously compromise safety, efficiency and quality of life. Magnitude of the problem was assessed among 51 type 2 diabetes patients by pure tone audiometry, in comparison with 51 age-matched non-diabetic controls. Glycaemic control, blood pressure, lipid profile and retinopathy were examined for any association to presence and extent of hearing loss. Glycaemic control in managed type 2 diabetics was not tight and all patients suffered hearing loss of some degree. Less than third of control suffered hearing loss in higher age and often with pre diabetic profile of blood sugar. Hyperglycaemia showed singularly strongest correlation to extent of hearing loss, while rising tendency in blood pressure came as close second risk factor. Retinopathy was strongly associated with extensive hearing loss. Triglycerides and VLDL profiles did and LDL or HDL profiles did not correlate to the extent of hearing losses. Duration of the diagnosed disease also showed no correlation. Mitochondrial dysfunction due to hyperglycaemia either directly or indirectly through free radical excess is appealing as basis for damage to high energy sensitive cochlear and neural cells. Hyper-coagulability may but atherosclerosis may not be a mode of contribution by altered lipid profile to hearing loss. Lose control of blood sugar, blood pressure, presence of microangiopathy, raised triglyceride signal a bad omen for hearing function.

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