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Year : 2010  |  Volume : 1  |  Issue : 3  |  Page : 2

Outcome of coronary artery bypass surgery in diabetic and non -diabetic patients: A comparative, retrospective study

Department of Clinical Research, Tehran Heart Center, Tehran University of Medical Science, Tehran, Iran

Correspondence Address:
M Shirzad
Department of Clinical Research, Teh ran Heart Center, Tehran University of Medical Science, Tehran, Iran

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Source of Support: None, Conflict of Interest: None

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Diabetes mellitus is a risk factor for adverse long-term outcome after medical therapy, PCI, or coronary artery bypass surgery. To assess the validity of this concern, we evaluated the effect of diabetes mellitus on in-hospital mortality and morbidity after coronary artery bypass grafting (CABG). Thirteen thousand eight hundred fifty seven patients (4389 diabetics and 9468 non-diabetics) were retrospectively analyzed after isolated CABG. Demographic and preoperative data and postoperative in-hospital mortality and morbidity were compared in both diabetic and non-diabetic groups. Analysis was performed in both univariate and multivariable logistic regression to compare the results. Diabetic patients were older than the non-diabetic population (mean age 59.2±8.7yrs versus 58.3±9.9yrs), included more women (37.6% vs 19.6%), had more postoperative superficial/deep sternal wound infection (0.6% vs 0.2 %), prolonged ventilation (3.2% vs 1.5%), cardiac arrest (1.3% vs 0.5%), stroke (0.6% vs 0.3%), renal dysfunction (1.5% vs 0.6%), coma (0.5% vs 0.1%), AF (6.5% vs 5.7%), and in- hospital mortality (1.4% versus 0.5%) (all p< 0.05). There were also significant differences for mean aortic cross-clamp and cardiopulmonary bypass times between diabetics and non-diabetics (43.74±14. 37 vs 41.89±15.76 mins and 73.10±24.05 vs 69.97±24.43 mins, respectively) (p<0.05). Logistic regression showed that there was a significant relationship between diabetes and postoperative superficial/deep sternal wound infection as well as prolonged ventilation and cardiac arrest, but it did not show any relationship between diabetes and in-hospital mortality. It seems that diabetes mellitus has a significant impact on postoperative superficial/deep sternal wound infection, prolonged ventilation, and cardiac arrest. But diabetic patients do not necessarily have an increased risk of in-hospital mortality and other complications.

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